Prevalence and Molecular Detection of Helicobacter pylori Virulence Genes Among Dyspeptic Patients Attending Gastroenterology Clinics in Nigeria
Helicobacter pylori infection is highly prevalent in developing countries and is associated with chronic gastritis, peptic ulcer disease, and gastric cancer. The pathogenicity of H. pylori is influenced by virulence genes such as cagA and vacA, which contribute to disease severity and clinical outcomes. Understanding the distribution of virulence-associated genes among local isolates is important for risk stratification and disease management. Despite the burden of H. pylori infection in Nigeria, limited molecular data exist regarding virulence gene profiles among infected patients.
