Occurrence of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in Poultry Farms and Associated Public Health Risks in Nigeria
Background
The use of antibiotics in poultry production has contributed to the emergence of antimicrobial-resistant bacteria with potential implications for human health. Extended-spectrum beta-lactamase-producing Enterobacteriaceae are of particular concern because of their resistance to commonly used antibiotics and ability to spread resistance genes across bacterial populations. Poultry farms may serve as reservoirs of resistant organisms that can be transmitted through food, the environment, or direct contact. This study seeks to investigate the occurrence and resistance characteristics of ESBL-producing Enterobacteriaceae in poultry production systems.
Research Objectives
- Determine the prevalence of ESBL-producing Enterobacteriaceae in poultry farms.
- Identify bacterial species carrying ESBL genes.
- Assess antimicrobial resistance patterns among isolates.
- Characterize ESBL-associated resistance genes.
- Evaluate farm management practices associated with resistance occurrence.
Research Questions
- What is the prevalence of ESBL-producing Enterobacteriaceae in poultry farms?
- Which bacterial species harbor ESBL genes?
- What are the resistance profiles of the isolates?
- Which ESBL genes are commonly detected?
- What farm practices are associated with resistance occurrence?
Suggested Methodology
A cross-sectional microbiological study will be conducted using poultry fecal and environmental samples collected from commercial farms. Standard culture techniques, antimicrobial susceptibility testing, and PCR-based gene detection will be performed. Statistical analyses will evaluate associations between farm practices and resistance patterns.
Suggested Sample
Keywords
Need Help With Data Analysis?
Get support with statistical analysis, dashboards, interpretation, Chapter 4 reporting, and public health research analytics.